Degradation behaviour of LAE442-based plate–screw-systems in an in vitro bone model

Degradation behaviour of LAE442-based plate–screw-systems in an in vitro bone model

Kategorien Zeitschriften/Aufsätze (reviewed)
Jahr 2015
Autoren Wolters, L., Besdo, S., Angrisani, N., Wriggers, P., Hering, B., Seitz, J., Reifenrath, J.:
Veröffentlicht in Materials Science and Engineering, Vol. 49 (2015), S. 305 - 315.

The use of absorbable implant materials for fixation after bone fracture helps to avoid a second surgery for implant removal and the risks and costs involved. Magnesium (Mg) is well known as a potential metallic material for degradable implants. The aim of the present in vitro study was to evaluate if degradable LAE442-based magnesiumplate–screw-systems are suitable candidates for osteosynthesis implants in load-bearing bones. The corrosion behaviourwas tested concerning the influence of different surface treatments, coatings and screwtorques. Steel plates and screws of the same size served as control. Plates without special treatment screwed on up to a specified torque of 15 cNm or 7 cNm, NaOH treated plates (15 cNm), magnesium fluoride coated plates (15 cNm) and steel plates as control (15 cNm) were examined in pH-buffered, temperature-controlled SBF solution for two weeks. The experimental results indicate that the LAE442 plates and screws coatedwith Magnesium fluoride revealed a lower hydrogen evolution in SBF solution as well as a lowerweight loss and volume decrease in μ-computed tomography (μCT). The nanoindentation and SEM/EDX measurements at several plate areas showed no significant differences. Summarized, the different screw torques did not affect the corrosion behaviour differently. Also the NaOH treatment seemed to have no essential influence on the degradation kinetics. The plates coatedwith magnesiumfluoride showed a decreased corrosion rate. Hence, it is recommended to consider this coating for the next in vivo study.

DOI 10.1016/j.msec.2015.01.019