ForschungPublications
Biomechanical properties of a novel biodegradable magnesium-based interference screw

Biomechanical properties of a novel biodegradable magnesium-based interference screw

Categories Zeitschriften/Aufsätze (reviewed)
Year 2016
Authors Ezechieli, M., Meyer, H., Lucas, A., Helmecke, P., Becher, C., Calliess, T., Windhagen, H., Ettinger, M.:
Published In Orthopedic Reviews, Vol. 8:6445 (2016), S. 71 - 74.
Description

Magnesium-based interference screws may be an alternative in anterior/posterior cruciate ligament reconstruction. The well-known osteoconductive effects of biodegradable magnesium alloys may be useful. It was the purpose of this study to evaluate the biomechanical properties of a magnesium based interference screw and compare it to a standard implant. A MgYREZr-alloy interference screw and a standard implant (Milagro®; De Puy
Mitek, Raynham, MA, USA) were used for graft fixation. Specimens were placed into a tensile loading fixation of a servohydraulic testing machine. Biomechanical analysis included pretensioning of the constructs at 20 N for 1
min following cyclic pretensioning of 20 cycles between 20 and 60 N. Biomechanical elongation was evaluated with cyclic loading of 1000 cycles between 50 and 200 N at 0.5 Hz. Maximum load to failure was 511.3±66.5 N for
the Milagro® screw and 529.0±63.3 N for magnesium-based screw (ns, P=0.57). Elongations after preload, during cyclical loading and during failure load were not different between the groups (ns, P>0.05). Stiffness
was 121.1±13.8 N/mm for the magnesiumbased screw and 144.1±18.4 for the Milagro® screw (ns, P=0.32). MgYREZr alloy interference screws show comparable results in biomechanical testing to standard implants and
may be an alternative for anterior cruciate reconstruction in the future.